Hitman is a 2007 action-thriller film directed by Xavier Gens from a screenplay by Skip Woods. Produced by Luc Besson, it is based on the video game series of the same name. The film stars Timothy Olyphant as Agent 47, a professional hitman engineered to be an assassin by the Organization. He becomes ensnared in a political conspiracy and finds himself pursued by both Interpol and the FSB. Dougray Scott and Olga Kurylenko star in supporting roles.

An international co-production between France, the United States and the United Kingdom, Hitman was released by 20th Century Fox in the US on November 21, 2007, followed by the UK on November 30 and France on December 26. The film received mostly negative reviews from critics, who criticized its convoluted plot but praised Olyphant's performance. Despite this, the film was a box office success, grossing $101.3 million against a $24 million budget. A sequel was canceled during the film's production due to its mostly negative reception, but the film was eventually followed by the reboot Hitman: Agent 47 in 2015.

Inside a heavily guarded facility, a group of young boys are given tattoos of bar codes on the backs of their shaved heads and are then trained in weapons, demolitions, unarmed combat, stamina, and strength to become professionally trained hitmen who operate around the globe. In the present day, Interpol agent Mike Whittier arrives home and is met at gunpoint by Agent 47. The two talk about 47's life as a professional hitman, raised and trained by a clandestine group known simply as the Organization.

Three months prior to that, 47 is completing a hit on a Nigerien warlord named Bwana Ovie. In a subsequent change of plans, 47 is told by his Organization handler, Diana Burnwood, that he is to kill his next target, Russian president Mikhail Belicoff, publicly instead of privately. Agent 47 completes his mission by shooting the man in the head, but before he can leave Russia, he is contacted by his superiors. He is mystified when told the hit was a failure and that Belicoff survived the attack on his life. The Organization notifies him of a witness to the assassination and orders him to intercept and kill her. However, when 47 realizes she has never seen him before, he does not shoot her; instead, he narrowly avoids an assassination attempt on himself by another agent and realizes he is being set up.

His employers send his location and identity to the FSB, but Diana secretly calls 47 and tips him off, revealing that Belicoff himself had ordered the hit. After escaping from his hotel, 47 intercepts Nika, Belicoff's mistress and the woman who supposedly witnessed his hit. He interrogates her and discovers that Belicoff had a double, who ordered the hit on the real Belicoff in order to take his place as the president of Russia. The Organization, hoping to gain influence with the new government, ordered 47 to kill Nika and then set him up to be erased and thus cover their tracks.

Nika and 47, attempting to leave Russia by train, are pursued by Organization agents, whom 47 subdues and kills in a sword fight. Whittier then attempts to arrest 47 himself, only to be easily overpowered. Nika persuades 47 to let Whittier go free, and Whittier is forced to leave Russia by FSB officer Yuri Marklov, who is overseeing the manhunt, for interfering. 47 contacts his associate, CIA officer Carlton Smith, to offer him a deal: 47 will kill Udre Belicoff (Mikhail's brother and a wealthy arms dealer and human trafficker) in exchange for a favour. Smith informs 47 that Udre had been planning something with a German gunrunner named Price.

47 and Nika travel to Istanbul, where 47 abducts Price, poses as him to meet Udre at a club, and kills him, forcing Belicoff's double to attend Udre's public funeral. 47 kidnaps Marklov and forces him to order his own agents to disrupt the funeral and create a distraction while 47, disguised as a soldier, deals with the imposter's bodyguards and kills him before Whittier arrives with backup from Interpol to take him into custody. Smith delivers on his end of the deal and has his operatives intercept the convoy that is transporting 47 to the airport, allowing the hitman to escape.

Back in Whittier's home, 47 threatens Whittier into notifying the police that he has killed (a fake) Agent 47. Nika is seen picking up an envelope containing the deed to a vineyard, a dream of hers to own. Agent 47 is watching her from afar, through the scope of a sniper rifle. Looking at the corpse of another agent lying at his feet, he muses that he had warned him (meaning the Organization) to leave her alone, and then walks away.