Hot-Rod and Reel! is a 1959 Warner Bros. Looney Tunes cartoon directed by Chuck Jones. The story was written by Michael Maltese, and the film score was composed by Milt Franklyn.

The short was released on May 9, 1959, and stars Wile E. Coyote and the Road Runner.

Wile E. Coyote (Famishius-Famishius) attempts several ways to get the Road Runner (Super-Sonicus-Tastius). The Road Runner reaches two outcroppings. When Wile E. tries it, the end of said outcropping comes off. Just when he thinks he is about to suffer gravity yet again, Wile E. is saved by a tree branch. He tries to go on the plateau nearby, only for the plateau to fall to a river. A fish nearby is spooked when Wile E. gets his newest scheme.

1. The Coyote races after the Road Runner with his new roller skates. When the Road Runner tries to trip the Coyote, Wile E., in time, leaps in the air and sticks his tongue out at the bird, but little does he know, he is about to fall off a cliff yet again. He ends up in the ground, with only his feet sticking out, as the wheels fall off one of the skates.

2. After getting an explosive camera kit, Wile E. prepares for his newest deception. The Road Runner is intrigued by the signs. When the Road Runner gets ready for his picture, the gun goes off on the Coyote instead. As the Road Runner speeds away, the dazed Wile E. sees the one flaw of his attempt: he forgot to take off the lens cap that was on the entire time.

3. As the Road Runner taunts the Coyote from above, Wile E. prepares a trampoline. However, when he jumps, he gets trapped inside like a burlap sack.

4. Now armed with a crossbow and dynamite, Wile E. prepares for his plan. However, when he lights the fuse and the Road Runner comes, the crossbow fires yet the dynamite is left behind to blow him up.

5. Now resorting to his best friend ACME, Wile E. receives a jet propelled pogo stick. However, when the Coyote prepares the pogo stick, it propels him to the cliff behind him. Down he goes again.