Ikwuano is a Local Government Area of Abia State, Nigeria. Its headquarters is in Isiala Oboro. The name 'Ikwuano' etymologically indicates that there are four different ancient kingdoms that make up the community called Ikwuano. These include Oboro, Ibere, Ariam/Usaka and Oloko.

The postal code of the area is 440. It is one of the five Local Government Areas that make up the Abia Central Senatorial District. As at 2024, the executive chairman is Dr. Anthony Nzeribe Nwaubani. Obi Aguocha currently serves as the Federal Representative representing Ikwuano/Umuahia North and South Federal Constituency at the House of Representatives. The member representing Ikwuano State Constituency at the Abia State House of Assembly is Engr. Boniface Isienyi.

The present Ikwuano Local Government Area was part of the Bende Division in the then Southern Province created by the British Colonial Government as part of their “Divide and Rule” system of government and administration towards the beginning of the 19th Century. This was as early as the time Calabar was the capital of Nigeria.

When the Southern province was further divided, Ikwuano still remained part of the Bende Division. The present Bende town was the administrative headquarters where the District Commissioner resided. The District Commissioner, Nwa D.C., as he was known and called held courts at Bende and Oloko. At this time what was later carved out as Aba Division was part of the Bende Division, under the jurisdiction of Nwa D. C. The present Umuahia township later replaced Bende as the administrative headquarters after the extension of the Nigerian rail line from Port-Harcourt to Enugu between 1915 and 1916.^{[unreliable source?]}

Ikwuano Local Government Area was among the new local government areas that were created on 27 August 1991 when the General Ibrahim Babangida's Administration created Abia State from the old Imo State. It was carved out of the defunct Ikwuano-Umuahia of the Old Imo State.

The Aba Women's Riot began in Oloko. The demonstration occurred when thousands of women of Igbo origin from Bende, Umuahia, Owerri and other regions in the South East made the trip to Oloko, one of the four principal communities of Ikwuano. The cause of this movement was due to the worry that a new taxation plan was being implemented that would demand women, most especially widows, to pay taxes which they were not mandated to pay earlier on.

Ikwuano is known for cultures and arts which include Ekpe, which is usually in January in the different Ikwuano communities coinciding with their respective market days, New Yam (Iri-Ji) and Afo Amaghi Onuma festivals. Their cultural dances are Eketensi Ritual dance, Oro, Ikperikpeogu (War Dance), Uko and so on. They also have Oba and Ekpe societies. Popular delicacies in Ikwuano include Ofe Achara, Ukazi Soup and Ugwu Soup. The predominant languages spoken in Ikwuano are Igbo and English languages. The four clans speak distinct Igbo dialects though mutually intelligible. Ikwuano brides are known to have some of the costliest bride prices in Igboland. Traditional marriages are held in high esteem.

It has an area of 281 km². It lies between the latitudes 5 24lN and 5 30lN and between the longitudes of 7 32lE and 7 37lE.