Indianapolis Marriott Downtown is a high-rise hotel in Indianapolis, Indiana. It was completed in 2001 and has 19 floors. It was the largest hotel in Indiana until surpassed by the JW Marriott Indianapolis in 2011. The Indianapolis Marriott Downtown features 650 guest rooms and 40,000 square feet (3,700 m²) of meeting/event space spread over 33 rooms.

According to the Indianapolis Business Journal, the Indianapolis Marriott Downtown has 365 full-time employees and was last renovated in 2017. As of 2020, four dining options were located in the hotel, including Conner's Kitchen + Bar, Rye Bar, Loaf + Vine Market, and Starbucks.