"Infinite Crisis" is a 2005–2006 comic book storyline published by DC Comics, consisting of an eponymous, seven-issue comic book limited series written by Geoff Johns and illustrated by Phil Jimenez, George Pérez, Ivan Reis, and Jerry Ordway, and a number of tie-in books. The main miniseries debuted in December 2005, and each issue was released with two variant covers: one by Pérez and one by Jim Lee and Sandra Hope.

The series storyline was a sequel to DC's 1985 limited series Crisis on Infinite Earths, which "rebooted" much of the DC continuity in an effort to fix 50 years of allegedly contradictory character history. It revisited characters and concepts from Crisis, including the existence of DC's Multiverse. Some of the characters featured were alternate versions of comic icons such as an alternate Superman named Kal-L, who came from a parallel universe called Earth-Two. A major theme was the nature of heroism, contrasting the often dark and conflicted modern-day heroes with memories of "lighter" and comparatively more noble and collegial heroes of American comic books' earlier days.

Infinite Crisis #1 was ranked first in the top 300 comics for October 2005 with pre-order sales of 249,265. This was almost double the second ranked comic House of M #7, which had pre-order sales of 134,429. Infinite Crisis #2 was also the top seller in top 300 comics for November 2005 with pre-order sales of 207,564.

The plot begins when, in Crisis on Infinite Earths, Kal-L (the Superman of pre-Crisis Earth-Two), the Superboy of Earth Prime, Alexander Luthor Jr. of pre-Crisis Earth-Three, and Lois Lane Kent of pre-Crisis Earth-Two voluntarily sequestered themselves in "paradise". DC officially began leading up to the new Crisis with a one-shot issue Countdown to Infinite Crisis, followed by four six-issue limited series that tied into and culminated in Infinite Crisis.

Once the Crisis was completed, DC used the One Year Later event to move the narratives of most of its DC Universe series forward by one year. The weekly series 52 began publication in May 2006, and depicts some of the events which occurred between Infinite Crisis and One Year Later.

In June 2008, a third series (Final Crisis), set immediately following the conclusion of Countdown, began.

Infinite Crisis was announced in March 2005. The event was kicked off with the release of Countdown to Infinite Crisis. Countdown to Infinite Crisis was followed by four six-issue limited series: The OMAC Project, Rann–Thanagar War, Day of Vengeance, and Villains United, as well as a four-part limited series DC Special: The Return of Donna Troy. These first four limited series each had a special tie-in issue, released at monthly intervals during the Infinite Crisis event.

As with many large-scale comic crossovers, Infinite Crisis featured a number of tie-ins. Before the event was announced, books such as Adam Strange and Identity Crisis were being described as part of bigger plans. After Countdown, several books were identified as tie-ins to the four mini-series. Thus, although Infinite Crisis itself is only seven issues long, its plot elements appeared in dozens of publications.