Isaac Garza Garza (June 3, 1853 – May 1, 1933) was a Mexican businessman who redirected to industry the interests of the Garza family which, according to Fortune Magazine, are the Mexican equivalent of the Rockefellers.

Isaac Garza Garza was a Mexican businessman who redirected to industry the interests of the Garza family which, according to Fortune Magazine, are the Mexican equivalent of the Rockefellers. He founded the Cuauhtémoc Brewery, later he was chairman of the Board of the Compañía Fundidora de Fierro y Acero de Monterrey, the Vidriera Group and the Cervecería Group. These companies were later the nucleus of what was called Grupo Monterrey, one of the most important industrial conglomerates in Mexico, integrated by two large consortiums: Grupo Industrial Alfa, initially led by his grandson, Bernardo Garza Sada, and Valores Industriales (VISA), initially led by another of his grandsons Eugenio Garza Lagüera.