James Guidry (born March 12, 1967) is an American former professional football quarterback who played five seasons in the Arena Football League (AFL) with the Dallas Texans, Milwaukee Mustangs, Florida Bobcats, Anaheim Piranhas and Portland Forest Dragons. He played college football at Texas A&I University. He was also a member of the Detroit Drive.

James Guidry was born on March 12, 1967. He was a three-year letterman for the Texas A&I Javelinas football of Texas A&I University from 1986 to 1988.

In August 1990, it was reported that Guidry had signed with a team in Barcelona, Spain.

Guidry was a member of the Detroit Drive during the 1993 Arena Football League season.

Guidry was traded to the Dallas Texans in June 1993.

After playing in Europe for several years, Guidry signed with the Milwaukee Mustangs in April 1996.

Guidry played for the Florida Bobcats in 1996.

Guidry was traded to the Anaheim Piranhas in March 1997. He was released by the Piranhas in April 1997.