The Japan Aerospace Exploration Agency (JAXA) (国立研究開発法人宇宙航空研究開発機構, Kokuritsu-kenkyū-kaihatsu-hōjin Uchū Kōkū Kenkyū Kaihatsu Kikō; lit. 'National Research and Development Agency Aerospace Research and Development Organisation') is the Japanese national air and space agency. Through the merger of three previously independent organizations, JAXA was formed on 1 October 2003. JAXA is responsible for research, technology development and launch of satellites into orbit, and is involved in many more advanced missions such as asteroid exploration and possible human exploration of the Moon. Its motto is One JAXA and its corporate slogan is Explore to Realize (formerly Reaching for the skies, exploring space).

On 1 October 2003, three organizations were merged to form the new JAXA: Japan's Institute of Space and Astronautical Science (ISAS), the National Aerospace Laboratory of Japan (NAL), and National Space Development Agency of Japan (NASDA). JAXA was formed as an Independent Administrative Institution administered by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) and the Ministry of Internal Affairs and Communications (MIC).

Before the merger, ISAS was responsible for space and planetary research, while NAL was focused on aviation research. ISAS had been most successful in its space program in the field of X-ray astronomy during the 1980s and 1990s. Another successful area for Japan has been Very Long Baseline Interferometry (VLBI) with the HALCA mission. Additional success was achieved with solar observation and research of the magnetosphere, among other areas.

NASDA, which was founded on 1 October 1969, had developed rockets, satellites, and also built the Japanese Experiment Module. The old NASDA headquarters were located at the current site of the Tanegashima Space Center, on Tanegashima Island, 115 kilometers south of Kyūshū. NASDA was mostly active in the field of communication satellite technology. However, since the satellite market of Japan is completely open, the first time a Japanese company won a contract for a civilian communication satellite was in 2005. Another prime focus of the NASDA body is Earth climate observation. NASDA also trained the Japanese astronauts who flew with the US Space Shuttles.

The Basic Space Law was passed in 2008, and the jurisdictional authority of JAXA moved from MEXT to the Strategic Headquarters for Space Development (SHSD) in the Cabinet, led by the Prime Minister. In 2016, the National Space Policy Secretariat (NSPS) was set up by the Cabinet.

JAXA was awarded the Space Foundation's John L. "Jack" Swigert Jr., Award for Space Exploration in 2008.

Planning interplanetary research missions can take many years. Due to the lag time between these interplanetary events and mission planning time, opportunities to gain new knowledge about the cosmos might be lost. To prevent this, JAXA began commencing smaller and faster missions from 2010 onward.

In 2012, new legislation extended JAXA's remit from peaceful purposes only to include some military space development, such as missile early warning systems. Political control of JAXA passed from MEXT to the Prime Minister's Cabinet Office through a new Space Strategy Office.