Joseph Quesada (/kəˈsɑːdə/; born January 12, 1962) is an American comic book artist, writer, editor, and television producer. He became known in the 1990s for his work on various Valiant Comics books, such as Ninjak and Solar, Man of the Atom. He also worked on numerous books for DC Comics and Marvel Comics, such as Batman: Sword of Azrael and X-Factor, before forming his own company, Event Comics, where he published his creator-owned character, Ash.

In 1998 he became an editor of Marvel Comics' Marvel Knights line, before becoming editor-in-chief of the company in 2000. He was named chief creative officer of Marvel Entertainment in 2010 and left his editor-in-chief role in January 2011, being replaced by Axel Alonso. His position was re-titled as executive vice president and creative director in October 2019. He left the company in 2022.

Quesada was born in New York City to Cuban-born parents, and grew up in the Jackson Heights neighborhood of Queens, 15 blocks from Shea Stadium, which his father helped build as part of the construction crew. The first comic book he became an ardent fan of was The Amazing Spider-Man, which he began reading around issue #98, the last issue of a historic anti-drug storyline, which garnered his father's approval. As the character resonated with him (in part because both grew up in Queens), Spider-Man remains a character he particularly enjoys drawing.

Quesada majored in illustration at the School of Visual Arts, from which he graduated with a BFA in 1984. Though he had drifted away from comics, having come to think of them as a child's medium, his interest in them was renewed at age 25 when a friend who learned of his interest in art showed him Frank Miller's The Dark Knight Returns.

Quesada's comics career began in 1990 when he was hired by DC Comics on the basis of his 12-page portfolio, which was composed of three three-page sequences, plus a cover for each. These included a Superman story intended to show reviewers from DC Comics that he could handle their characters; an X-Men sequence to display both his ability to depict the characters of Marvel Comics and his ability to handle groups of characters; and a vignette of two people having coffee, which Quesada included to show his ability to illustrate non-superhero stories.

Among Quesada's earliest widely distributed work was for Valiant Comics, specifically penciled interiors and covers for Ninjak, Solar, Man of the Atom and others. His art was heavily influenced by Alex Toth, Mike Mignola, and Alphonse Mucha. At DC Comics, he and writer Jack C. Harris co-created an updated version of the Golden Age character The Ray. Quesada co-created the character Azrael with writer Dennis O'Neil for the 1992 Batman: Sword of Azrael miniseries.

Later, Quesada and his inking partner Jimmy Palmiotti, formed a publishing company, Event Comics, and co-created Ash, a firefighter with superpowers. Quesada cites his editorial experience with Event, and the creators he formed relationships with during that period as that which best prepared him for the later role of Marvel's editor-in-chief.

In 1998, Marvel Comics, which had just filed for Chapter 11 bankruptcy, asked Quesada to work for Marvel in a more exclusive capacity, and contracted him and his partners to produce a line of Marvel books dubbed Marvel Knights. As editor of Marvel Knights, Quesada worked on a number of low-profile characters such as Daredevil, Punisher, The Inhumans, and Black Panther, encouraging experimentation and using his contacts in the independent comics world to bring in creators such as David W. Mack, Mike Oeming, Brian Michael Bendis, Garth Ennis, and Steve Dillon. Quesada also illustrated a Daredevil story written by film director Kevin Smith.