Gutenberg moved to Strasbourg, a city known for its craftsmanship and trade. This move marked a significant turning point as it provided him with a new environment to pursue his inventive ideas.

Historical accounts suggest Gutenberg was involved in various crafts and trades in Strasbourg, including metalworking, jewelry making, and polishing gemstones. These activities honed his skills and provided him with a deep understanding of metallurgy, which would prove essential for his printing innovations.

Gutenberg entered into a partnership with Andreas Dritzehn, Andreas Heilmann, and Imer Frieburg for a project described as 'arts and adventures'. While the specific nature of the project remains debated, many believe it involved early experiments related to printing or other mechanical inventions. The partnership dissolved after Dritzehn's death, leading to legal disputes.

Following Andreas Dritzehn's death, his heirs sued Gutenberg, seeking a share of the profits from the partnership. This lawsuit provides valuable insights into Gutenberg's secretive experiments and confirms the existence of early printing-related activities. Witnesses testified about the existence of forms, presses, and printing materials, although their exact function was not fully understood.