Jokhio (Sindhi: جوکيو) is a Sindhi Sammat tribe found in Sindh, Pakistan. The Jokhio were considered a powerful tribe and held great political importance in the British Raj Sindh and were granted Jagir by the Raj Government. The Jokhio tribe is also notable for Chaukhandi tombs, a centuries-old monument known for its sandstone carvings. The Sangurs claim affinity with the Jokhio.

There are five sub-tribes of Jokhia: Teebhar, Bandicho, Sālār, Burfat and Bhand.^{[citation needed]}

Other Jokhia clans are: Achha, Achhia, Arti, Aripota, Begani, Dhagra, Desrani, Dalilani, Daya, Esapota, Gaad, Halani, Hamirka, Jarani, Kalipota, Lākhani, Musa, Marmat, Qandarpota, Rabai, Saeedpota (Sethpota), Shahdadani, Saheriani, Sakhpota, Shahiani, Sainani, Sakhani, Tajpota, Tahriani, Wasandani.^{[citation needed]}