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The eponymous "Comby's sign" is named after him, which is an early indication of measles characterized by thin whitish patches on the gums and buccal mucous membrane.[2]
With Antoine Marfan (1858–1942) and Jacques-Joseph Grancher (1843–1907), he published the influential Traité des maladies de l’enfance (Treatise of the Diseases of Childhood). Other publications and translated works of his include:
Étiologie et prophylaxie du rachitisme, 1885 - Etiology and prevention of rachitis.
Étiologie et prophylaxie de la scrofule dans la première enfance, 1885 - Etiology and prevention of scrofula in infancy.
Le rachitisme, 1892, in Spanish as El raquitismo 1895 - Rachitis.