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KLK11
Kallikrein-11 is a protein that in humans is encoded by the KLK11 gene.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in two transcript variants encoding two different isoforms which are differentially expressed.
\* Shigemasa K, Gu L, Tanimoto H, O'Brien TJ, Ohama K (April 2004). "Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer". Clinical Cancer Research. 10 (8): 2766–2770. doi:10.1158/1078-0432.CCR-03-0269. PMID 15102682. S2CID 1192794.
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KLK11
Kallikrein-11 is a protein that in humans is encoded by the KLK11 gene.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in two transcript variants encoding two different isoforms which are differentially expressed.
\* Shigemasa K, Gu L, Tanimoto H, O'Brien TJ, Ohama K (April 2004). "Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer". Clinical Cancer Research. 10 (8): 2766–2770. doi:10.1158/1078-0432.CCR-03-0269. PMID 15102682. S2CID 1192794.