The Khamseh Arabs are an Arab nomadic and pastoral tribe of Fars province in Iran. They are a part of the Khamseh confederation. They speak a dialect of Central Asian Arabic. Their population numbers about 200,000.

The two Arab tribes in Fars province are Sheybani and Jabbareh.

The Sheybani (or Sheibani) migrated to Iran before the other group. At first they settled in Khorasan and later migrated to Fars district. A group of them live in Sheyban city of Bavi County in Khuzestan.

The Jabbareh settled in Fars say they are descendants of Jabir ibn Abd Allah, a companion of Muhammad. Their ancestor Sheikh Jinaah migrated to Fars and married a Sheybani girl, naming his descendants "Jabbareh".

Khamseh Arabs speak a dialect of Central Asian Arabic closely related to Uzbeki Arabic. Their dialect is hard for other Arabic speakers to understand. It has no relations to Gulf Arabic.^{[failed verification]}

Khamseh Arabs are mostly Shia Muslims.^{[better source needed]}