King of Fighters R-2 (KOF R-2) is a 1999 fighting video game released by SNK for the Neo Geo Pocket Color handheld system. It is the sequel to King of Fighters R-1 and is part of The King of Fighters series. Like most other games in the series, King of Fighters R-2 features various SNK characters; this game, which features the same story as The King of Fighters '98, has the main character going up against Rugal Bernstein, who is creating clones of the main characters.

A port for Nintendo Switch was released on August 7, 2020, which was additionally included as part of Neo Geo Pocket Color Selection Vol. 1 in 2021.

King of Fighters R-2 brings back most of King of Fighters R-1's gameplay, bringing back Singleplay and Teamplay, and the VS mode using a link cable. The Making mode is a new mode which lets the player customize their fighter and send them on a quest to defeat Rugal Bernstein. Also the player can connect with the Dreamcast game King of Fighters '99 Dream Match. It has all the starting characters from King of Fighters R-1 except Chizuru Kagura and Kim Kaphwan, replacing them with Saisyu Kusanagi and Kasumi Todoh.

King of Fighters R-2 on Nintendo Switch received "mixed or average reviews" according to review aggregator Metacritic.

In 2023, Time Extension identified King of Fighters R-2 as one of the best games for the NGPC.