Lester William Polsfuss is born in Waukesha, Wisconsin, to George and Evelyn Polsfuss. Early exposure to music comes through his mother, who played piano.

Demonstrates an early aptitude for both music and mechanics, taking apart radios and phonographs to understand how they worked. Develops a fascination with sound and amplification.

Frustrated by the limitations of playing guitar and harmonica simultaneously, Les invents a harmonica holder, a device still used today by musicians around the world.

Begins performing professionally as a hillbilly guitarist, playing country and western music at local venues. He adopts the stage name 'Red Hot Red' and later 'Rhubarb Red'.

Starts experimenting with amplifying sound, building his own microphones and experimenting with different pickups on guitars. These early experiments lay the groundwork for his later innovations.

Performs on KMOX radio in St. Louis, further honing his skills and gaining exposure to a wider audience. He gains experience playing various genres, including jazz and pop.

Moves to Chicago to pursue a career in jazz music, joining the Rube Tronson's Texas Cowboys and later forming his own trio.

Forms the Les Paul Trio, a jazz group that begins to gain popularity through radio performances and club dates. This marks a significant step in his transition from country to jazz music.