List of cutaneous conditions associated with internal malignancy

This is a list of cutaneous conditions associated with internal malignancy; skin markers of internal cancer.^[1] It does not include skin infections associated with cancer or cancers that spread to skin.^[1] Some have stronger associations with cancers than others.^[2]

Cutaneous conditions associated with internal benign tumors and/or malignancies
Cutaneous condition	Internal malignancy
Erythema gyratum repens	Lung cancer
Hypertrichosis lanuginosa acquisita	Lung cancer
Paraneoplastic pemphigus	Non-Hodgkin lymphoma^{[nb 1]} Chronic lymphocytic leukemia Castleman's disease^{[nb 1]} Sarcoma Thymoma
Tripe palms	Lung cancer
Tripe palms with acanthosis nigricans	Stomach cancer
Pityriasis rotunda	Hepatocellular carcinoma
Migratory thrombophlebitis	Pancreatic adenocarcinoma
Leser–Trélat sign	Gastrointestinal adenocarcinoma
Acquired ichthyosis	Hodgkin disease
Pityriasis rotunda	Hepatocellular carcinoma
Paraneoplastic pigmentation	Small cell bronchial carcinoma
Acrokeratosis paraneoplastica	Squamous cell carcinoma of the upper respiratory or gastrointestinal tracts
Necrolytic migratory erythema	Glucagon secreting pancreatic islet cell adenoma
Dermatomyositis	Lung cancer in men, breast and gynaecological tumours in women and colorectal cancers in both sexes
Scleroderma‐like skin changes	Carcinoid syndrome
Paraneoplastic pemphigus	B‐cell proliferations and thymoma or thymoma‐like neoplasms; specifically Non Hodgkin's lymphoma (42%)
Dermatitis herpetiformis	Lymphoma
Porphyria cutanea tarda and variegate porphyrias	Hepatocellular Carcinoma
Erythroderma and exfoliative dermatitis	Mycosis fungoides or Sézary syndrome
Pyoderma gangrenosum	Hematological malignancy
Sweet syndrome	Hematological malignancy

Footnotes

^ ^a ^b Non-Hodgkin lymphoma is the most common cause of paraneoplastic pemphigus in adults. Castleman's disease is the most common cause of paraneoplastic pemphigus in children.

References

^ ^a ^b Wick, Mark R.; Patterson, James W. (July 2019). "Cutaneous paraneoplastic syndromes". Seminars in Diagnostic Pathology. 36 (4): 211–228. doi:10.1053/j.semdp.2019.01.001. ISSN 0740-2570. PMID 30736994.
^ Fonia, Athina; Baran, Robert (2021). "Cutaneous paraneoplastic syndromes with nail involvement". In Lipner, Shari (ed.). Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics. Elsevier. pp. 175–182. ISBN 978-0-323-70924-8.

Bibliography

Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
James, William D.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.

[ex01a-3] Non-Hodgkin lymphoma is the most common cause of paraneoplastic pemphigus in adults. Castleman's disease is the most common cause of paraneoplastic pemphigus in children.

[Wick2019-1] Wick, Mark R.; Patterson, James W. (July 2019). "Cutaneous paraneoplastic syndromes". Seminars in Diagnostic Pathology. 36 (4): 211–228. doi:10.1053/j.semdp.2019.01.001. ISSN 0740-2570. PMID 30736994.

[Fonia2021-2] Fonia, Athina; Baran, Robert (2021). "Cutaneous paraneoplastic syndromes with nail involvement". In Lipner, Shari (ed.). Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics. Elsevier. pp. 175–182. ISBN 978-0-323-70924-8.

[1]

[2]

[nb 1]

List of cutaneous conditions associated with internal malignancy

Hub talks

List of cutaneous conditions associated with internal malignancy

List of cutaneous conditions associated with internal malignancy

Hub rules

List of cutaneous conditions associated with internal malignancy

Hub overview

Add your contribution

Inside this hub

Media Collections

Timelines

Articles

Notes collections

Notes

Days in Chronicle

Root Wikipedia Article

List of cutaneous conditions associated with internal malignancy

Footnotes

See also

References

Bibliography

Add your contribution

Related Hubs