Meta-Tyramine

meta-Tyramine, also known as m-tyramine and 3-tyramine, as well as 3-hydroxyphenethylamine, is an endogenous trace amine neuromodulator and a structural analog of phenethylamine. It is a positional isomer of para-tyramine, and similarly to it, has effects on the adrenergic and dopaminergic systems.

meta-Tyramine is produced in humans via aromatic amino acid decarboxylase-mediated metabolism of meta-tyrosine. meta-Tyramine can be metabolized into dopamine via peripheral or brain CYP2D6 enzymes in humans.