Homeobox protein Meis1 is a protein that in humans is encoded by the MEIS1 gene.

Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.

MEIS1 has been shown to interact with PBX1 and HOXA9.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.