In physics, M-theory is a theory that unifies all consistent versions of superstring theory. Edward Witten first conjectured the existence of such a theory at a string theory conference at the University of Southern California in 1995. Witten's announcement initiated a flurry of research activity known as the second superstring revolution. Prior to Witten's announcement, string theorists had identified five versions of superstring theory. Although these theories initially appeared to be very different, work by many physicists showed that the theories were related in intricate and nontrivial ways. Physicists found that apparently distinct theories could be unified by mathematical transformations called S-duality and T-duality. Witten's conjecture was based in part on the existence of these dualities and in part on the relationship of the string theories to a field theory called eleven-dimensional supergravity.

Although a complete formulation of M-theory is not known, such a formulation should describe two- and five-dimensional objects called branes and should be approximated by eleven-dimensional supergravity at low energies. Modern attempts to formulate M-theory are typically based on matrix theory or the AdS/CFT correspondence. According to Witten, M should stand for "magic", "mystery" or "membrane" according to taste, and the true meaning of the title should be decided when a more fundamental formulation of the theory is known.

Investigations of the mathematical structure of M-theory have spawned important theoretical results in physics and mathematics. More speculatively, M-theory may provide a framework for developing a unified theory of all of the fundamental forces of nature. Attempts to connect M-theory to experiment typically focus on compactifying its extra dimensions to construct candidate models of the four-dimensional world, although so far none have been verified to give rise to physics as observed in high-energy physics experiments.

One of the deepest problems in modern physics is the problem of quantum gravity. The current understanding of gravity is based on Albert Einstein's general theory of relativity, which is formulated within the framework of classical physics. However, nongravitational forces are described within the framework of quantum mechanics, a radically different formalism for describing physical phenomena based on probability. A quantum theory of gravity is needed in order to reconcile general relativity with the principles of quantum mechanics, but difficulties arise when one attempts to apply the usual prescriptions of quantum theory to the force of gravity.

String theory is a theoretical framework that attempts to reconcile gravity and quantum mechanics. In string theory, the point-like particles of particle physics are replaced by one-dimensional objects called strings. String theory describes how strings propagate through space and interact with each other. In a given version of string theory, there is only one kind of string, which may look like a small loop or segment of ordinary string, and it can vibrate in different ways. On distance scales larger than the string scale, a string will look just like an ordinary particle, with its mass, charge, and other properties determined by the vibrational state of the string. In this way, all of the different elementary particles may be viewed as vibrating strings. One of the vibrational states of a string gives rise to the graviton, a quantum mechanical particle that carries gravitational force.

There are several versions of string theory: type I, type IIA, type IIB, and two flavors of heterotic string theory (SO(32) and E₈×E₈). The different theories allow different types of strings, and the particles that arise at low energies exhibit different symmetries. For example, the type I theory includes both open strings (which are segments with endpoints) and closed strings (which form closed loops), while types IIA and IIB include only closed strings. Each of these five string theories arises as a special limiting case of M-theory. This theory, like its string theory predecessors, is an example of a quantum theory of gravity. It describes a force just like the familiar gravitational force subject to the rules of quantum mechanics.

In everyday life, there are three familiar dimensions of space: height, width and depth. Einstein's general theory of relativity treats time as a dimension on par with the three spatial dimensions; in general relativity, space and time are not modeled as separate entities but are instead unified to a four-dimensional spacetime, three spatial dimensions and one time dimension. In this framework, the phenomenon of gravity is viewed as a consequence of the geometry of spacetime.

In spite of the fact that the universe is well described by four-dimensional spacetime, there are several reasons why physicists consider theories in other dimensions. In some cases, by modeling spacetime in a different number of dimensions, a theory becomes more mathematically tractable, and one can perform calculations and gain general insights more easily. There are also situations where theories in two or three spacetime dimensions are useful for describing phenomena in condensed matter physics. Finally, there exist scenarios in which there could actually be more than four dimensions of spacetime which have nonetheless managed to escape detection.