Maniac is an American psychological black comedy drama television miniseries that premiered on Netflix on September 21, 2018, after being announced in 2016. Patrick Somerville created the series and Cary Joji Fukunaga directed, basing it very loosely on the 2015 Norwegian television series of the same name (starring co-creator Espen PA Lervaag) while drawing inspiration from many more famous films. The 10-episode series stars Emma Stone, Jonah Hill, Justin Theroux, Sonoya Mizuno, Gabriel Byrne, and Sally Field. The plot follows two strangers who connect during a mind-bending pharmaceutical trial set in a retro-future New York City.

The series received positive reviews from critics upon release, with many praising its visuals, direction, and acting, particularly the performances of Stone and Hill. The series received multiple accolades, including nominations for Stone's performance—both at the 23rd Satellite Awards and the 25th Screen Actors Guild Awards—and for the series's overall writing—at the 71st Writers Guild of America Awards.

Maniac follows Annie Landsberg and Owen Milgrim, two strangers who connect during a risky, psychologically intense, twelve-person, mind-bending pharmaceutical trial conducted by Neberdine Pharmaceutical Biotech (NPB). The experiment, originally overseen by Dr. Robert Muramoto and Dr. Azumi Fujita, later falls under the purview of the study's original designer, the eccentric Dr. James K. Mantleray. Together, Annie and Owen go on a mind-bending odyssey through various hallucinatory worlds.

In addition to English, the original voicework features spoken Japanese and Icelandic, and (to a lesser extent) French. Netflix offers at least five different dubbings and five different subtitle options in different languages.

Maniac features 10 episodes, each running between 26–47 minutes. All episodes to the miniseries were released simultaneously on September 21, 2018.

The series was officially announced in March 2016, with Netflix ordering the production straight-to-series that same month. On March 18, 2016, it was announced that Paramount Television and Anonymous Content were producing a television series to be directed by Cary Joji Fukunaga. The half-hour dark comedy series was reported to be executive produced by Fukunaga, Emma Stone, Jonah Hill, Michael Sugar, and Doug Wald. Ashley Zalta was also announced as a co-executive producer. At the time, the series was being shopped to various networks and was searching for a writer. Less than a week later, it was announced that Netflix was finalizing a deal for a straight-to-series order for a first season consisting of ten episodes. On October 21, 2016, it was announced that Patrick Somerville would write the series. On July 29, 2018, it was announced during the annual Television Critics Association's summer press tour that the series would premiere on September 21, 2018.

Alongside the initial series announcement, it was reported that Emma Stone and Jonah Hill were finalizing deals to star in the series. In August 2017, it was announced that Sonoya Mizuno had been cast as a series regular and that Justin Theroux and Julia Garner would appear in a recurring capacity. On September 13, 2017, it was reported that Jemima Kirke had been cast in a recurring role. On October 5, 2017, it was announced that Sally Field had joined the cast in a recurring role. On February 23, 2018, it was reported Billy Magnussen had been cast in the series.

Principal photography for the series began on August 15, 2017, in New York City and was expected to conclude by the end of November 2017.