Maple Heights High School is a public high school located in Maple Heights, Ohio, southeast of Cleveland, Ohio. It graduated its first class in 1925. It was the first high school in America to offer a credit class in popular culture studies, created in 1975. It also offered a broadcast journalism class, Television Journalism, which produced a long-running public-access television cable TV program entitled Maple Schools Today, which ran on several Cleveland Ohio cable outlets from 1984 through 2002.

A completely new high school building opened in 2013, replacing one that dated back 90 years. A new stadium with artificial turf and an all-weather track opened in 2014.

Maple Heights High School athletics is best known for the success of the boys' wrestling teams. They won 10 state championships in a 19-year period from 1956–1974. They were led by legendary coach Mike Milkovich. Milkovich played a role in a sports brawl that led eventually to a U.S. Supreme Court case, Milkovich v. Lorain Journal Co., an important free speech case.

The team nickname is the Mustangs.