Marc Andreessen did not seek reelection at the 2018 Annual Meeting of Stockholders for Hewlett Packard Enterprise. His time on the board was marked by some criticism regarding certain company decisions.

An investor group including Andreessen Horowitz acquired a majority stake in Skype at a valuation of $2.75 billion. This was considered a risky investment at the time but proved highly successful when Microsoft bought Skype for $8.5 billion in May 2011.

Marc Andreessen and Ben Horowitz officially announced the formation of their venture capital firm, Andreessen Horowitz, in Silicon Valley. This marked a significant transition in their careers, moving from angel investors to formal venture capitalists with a larger fund and greater influence in the tech industry. The firm quickly became one of the most prominent venture capital firms in Silicon Valley, known for its investments in high-growth technology companies.