Marvel Strike Force is a turn-based role-playing mobile game by FoxNext (later acquired by Scopely) for Android, iOS, and iPadOS platforms. The game was launched worldwide on March 28, 2018, and is primarily set in the Marvel Universe.

The Earth has fallen under siege by sinister forces led by Ultimus. Agents of S.T.R.I.K.E. (Special Tactical Reserve for Interdimensional Key Events) have been called to assemble squads of heroes and villains to combat Ultimus' legions, that includes mind-controlled versions of the heroes and villains from alternate universes, before Earth falls under Ultimus' control.

In addition to this main storyline, special sub-plot events are also released, loosely based on recent Marvel Cinematic Universe films that have been released, starting with Avengers: Infinity War.

Marvel Strike Force allows players to collect Marvel Universe characters from both the heroes and villains and generic characters from large organizations such as S.H.I.E.L.D., the Hand, and Hydra, and use them to fight in turn-based battles. Similar to the fighting game Marvel: Contest of Champions, characters fall into one of several classes. There are multiple ways to collect characters: some are given to players immediately, whereas others are gained via gameplay or as in-game rewards in the form of shards that are earned by players to unlock and or promote their characters. Shards can either be earned from winning battles or bought from a shop. Players level up their user level by gaining experience, which is earned through daily quests and battles.

Battles are divided up into rounds, with the character with the highest speed attribute going first. Each team consists of up to five characters (though some AI teams in raids can have more characters) who battle until defeated or reinforcements enter. Battles are turn-based, based on the speed attribute, where the combatants apply healing and various buffs to their own team and damage and debuffs to the opponent.

Players may join alliances that form the main group inside of the game, which can include up to 24 players and be private or open. Alliances allow players to play in raids and wars and to access alliance milestones. These alliances can be created by any player or created by the game. All players must be in an alliance, so if a player leaves or is kicked from an alliance, the game will assign a new one.

Characters usually appear in their attire from the existing comics; a costume currency is available for purchasing attire for certain characters based on their Marvel Cinematic Universe appearances, old comic appearances or other notable media appearances. The attire sets have no bearing on the characters' moves, they are purely cosmetic.

The main game modes are Arena, Blitz, Raids, Alliance War, Real Time Arena, Cosmic Crucible, Alliance War, Campaign, Challenges, Dark Dimension, Scourges, and Sagas. The first four of those have their own currencies that can be spent on character shards or items. All modes are played versus a computer-controlled AI, except Real Time Arena, where the combatants are other players. This includes the Arena, Blitz, Cosmic Crucible, and Alliance War battles, in which the AI controls a player-created team.