Matteo Jorgenson (/ˈdʒɔːrɡɪnsən/ JOR-ghin-sən; born July 1, 1999) is an American professional cyclist who currently rides for UCI WorldTeam Visma–Lease a Bike. Known for his prowess in the mountains, he is a two-time winner of Paris–Nice.

Jorgenson was born in Walnut Creek, California, grew up in Boise, Idaho and credits BYRDS (Boise Young Rider Development Squad) for his start in cycling.

Jorgenson had an active 2022 Tour de France and was involved in several breakaways including on stages 10 and 16. Late in stage 16, he was trying to chase down the lead rider Hugo Houle when he crashed while rounding a sharp corner. Despite the crash, he was still able to finish fourth on the stage.

In the 2023 Tour de France, Jorgenson was involved in a 14-man breakaway on stage 9. With around 47 km remaining of the stage, he went clear from the group, leading the stage for most of the climb up the Puy de Dôme. However, within the final 500 metres, he was passed by Michael Woods and others, ultimately finishing fourth. He had to abandon the Tour a few days later, however, due to injuries suffered during a crash.

Jorgenson won the 2024 Paris–Nice, becoming the first American to win the race since Floyd Landis in 2006. His win was in significant part due to him being in a three-man breakaway on Stage 6, where they finished more than 50 seconds ahead of most of the race favorites.

Jorgenson signed for Team Jumbo-Visma in 2023, for three years.

Jorgenson placed second in the 2024 Criterium du Dauphine. He started the final stage over a minute behind Primož Roglič and attacked on the final climb. With Roglič unable to hold his wheel, Jorgenson and Carlos Rodríguez gained 56 seconds on the leader. With time bonuses, Jorgenson finished the race 8 seconds behind Roglič. Jorgenson also rode in the 2024 Tour de France, in which he finished 8th in the general classification.

Jorgenson extended his contract with Visma-Lease a Bike in 2025, staying with the team until at least 2029.