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Medical prescription
A prescription in the medical context, often abbreviated ℞ or Rx, is a formal communication from physicians or other registered healthcare professionals to a pharmacist, authorizing them to dispense a specific prescription drug for a specific patient. Historically, it was a physician's instruction to an apothecary listing the materials to be compounded into a treatment—the symbol ℞ (a capital letter R, crossed to indicate abbreviation) comes from the first word of a medieval prescription, Latin recipe (lit. 'take thou'), that gave the list of the materials to be compounded. Requirements for content, who may prescribe, and how prescriptions are transmitted vary by country; many jurisdictions use electronic prescribing systems.
In law, a prescription in the medical context is a written or electronic order for a medicinal product or medical device issued by a health professional—such as a physician, physician assistant, dentist, or veterinarian—who is legally entitled to prescribe within the jurisdiction where it is issued. In pharmacy usage, the term prescription generally refers to instructions for medicines that patients obtain from a pharmacy or doctor's office and take themselves outside the hospital. This contrasts with medication orders, which are recorded in hospital or institutional charts to guide nurses and other staff in administering medicines directly to inpatients.
Prescriptions may be issued on paper, electronically, or, where it is permitted, verbally (e.g., by telephone). Paper prescriptions normally require the prescriber's handwritten signature and the date of issue. In some jurisdictions, a digital signature may be accepted, while prescriptions for controlled drugs often carry additional legal requirements, such as a handwritten signature, specified wording, or security features. Electronic prescriptions are accepted in many jurisdictions, and verbal prescriptions, when accepted, are subject to restrictions and read-back procedures to reduce error. The content of a prescription includes the name and address of the prescribing provider and any other legal requirements, such as a registration number (e.g., a DEA number in the United States). Unique to each prescription is the name of the patient. In the United Kingdom and Ireland, the patient's name and address must also be recorded. Each prescription is dated, and some jurisdictions may place a time limit on the prescription. Due to the addictive properties of certain drugs, incidents where security hackers have compromised online prescription accounts and employees have forged paper scripts to be sold on the black market have occurred. In the past, prescriptions contained instructions for the pharmacist to use for compounding the pharmaceutical product, but most prescriptions now specify pharmaceutical products that were manufactured and require little or no preparation by the pharmacist.[citation needed] Prescriptions also contain directions for the patient to follow when taking the drug. These directions are printed on the label of the pharmaceutical product.
The word prescription, from pre- ('before') and script ('writing, written'), refers to the fact that the prescription is an order that must be written down before a drug can be dispensed. Those within the industry will often call prescriptions simply "scripts". The symbol "℞", sometimes transliterated as "Rx" or "Rx", is recorded in 16th century manuscripts as an abbreviation of the late Latin instruction recipe, meaning 'receive'. Originally abbreviated Rc, the later convention of using a slash to indicate abbreviation resulted in an R with a straight stroke through its right "leg". Medieval prescriptions invariably began with the instruction from the physician to the apothecary to "take" certain materials and compound them in specified ways.
Every prescription contains who prescribed the prescription, who the prescription is valid for, and what is prescribed. Some jurisdictions, drug types or patient groups require additional information as explained below.
Many brand name drugs have cheaper generic drug substitutes that are therapeutically and biochemically equivalent. Prescriptions will also contain instructions on whether the prescriber will allow the pharmacist to substitute a generic version of the drug. This instruction is communicated in a number of ways. In some jurisdictions, the preprinted prescription contains two signature lines: one line has "dispense as written" printed underneath; the other line has "substitution permitted" underneath. Some have a preprinted box "dispense as written" for the prescriber to check off (but this is easily checked off by anyone with access to the prescription). In other jurisdictions, the protocol is for the prescriber to handwrite one of the following phrases: "dispense as written", "DAW", "brand necessary", "do not substitute", "no substitution", "medically necessary", "do not interchange". In Britain's National Health Service, doctors are reminded that money spent on branded rather than generic drugs is consequently not available for more deserving cases.
The dose regimen is the planned schedule for administering a drug to a patient. It specifies the amount of drug given, how often it is administered, and the duration of treatment. The aim is to keep drug levels within the therapeutic range while avoiding adverse effects. A dose regimen typically includes:
Selection of an appropriate dose regimen is important for achieving therapeutic benefit. Incorrect dosing schedules may lead to treatment failure or drug toxicity, especially for medicines with a narrow therapeutic index.
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Medical prescription
A prescription in the medical context, often abbreviated ℞ or Rx, is a formal communication from physicians or other registered healthcare professionals to a pharmacist, authorizing them to dispense a specific prescription drug for a specific patient. Historically, it was a physician's instruction to an apothecary listing the materials to be compounded into a treatment—the symbol ℞ (a capital letter R, crossed to indicate abbreviation) comes from the first word of a medieval prescription, Latin recipe (lit. 'take thou'), that gave the list of the materials to be compounded. Requirements for content, who may prescribe, and how prescriptions are transmitted vary by country; many jurisdictions use electronic prescribing systems.
In law, a prescription in the medical context is a written or electronic order for a medicinal product or medical device issued by a health professional—such as a physician, physician assistant, dentist, or veterinarian—who is legally entitled to prescribe within the jurisdiction where it is issued. In pharmacy usage, the term prescription generally refers to instructions for medicines that patients obtain from a pharmacy or doctor's office and take themselves outside the hospital. This contrasts with medication orders, which are recorded in hospital or institutional charts to guide nurses and other staff in administering medicines directly to inpatients.
Prescriptions may be issued on paper, electronically, or, where it is permitted, verbally (e.g., by telephone). Paper prescriptions normally require the prescriber's handwritten signature and the date of issue. In some jurisdictions, a digital signature may be accepted, while prescriptions for controlled drugs often carry additional legal requirements, such as a handwritten signature, specified wording, or security features. Electronic prescriptions are accepted in many jurisdictions, and verbal prescriptions, when accepted, are subject to restrictions and read-back procedures to reduce error. The content of a prescription includes the name and address of the prescribing provider and any other legal requirements, such as a registration number (e.g., a DEA number in the United States). Unique to each prescription is the name of the patient. In the United Kingdom and Ireland, the patient's name and address must also be recorded. Each prescription is dated, and some jurisdictions may place a time limit on the prescription. Due to the addictive properties of certain drugs, incidents where security hackers have compromised online prescription accounts and employees have forged paper scripts to be sold on the black market have occurred. In the past, prescriptions contained instructions for the pharmacist to use for compounding the pharmaceutical product, but most prescriptions now specify pharmaceutical products that were manufactured and require little or no preparation by the pharmacist.[citation needed] Prescriptions also contain directions for the patient to follow when taking the drug. These directions are printed on the label of the pharmaceutical product.
The word prescription, from pre- ('before') and script ('writing, written'), refers to the fact that the prescription is an order that must be written down before a drug can be dispensed. Those within the industry will often call prescriptions simply "scripts". The symbol "℞", sometimes transliterated as "Rx" or "Rx", is recorded in 16th century manuscripts as an abbreviation of the late Latin instruction recipe, meaning 'receive'. Originally abbreviated Rc, the later convention of using a slash to indicate abbreviation resulted in an R with a straight stroke through its right "leg". Medieval prescriptions invariably began with the instruction from the physician to the apothecary to "take" certain materials and compound them in specified ways.
Every prescription contains who prescribed the prescription, who the prescription is valid for, and what is prescribed. Some jurisdictions, drug types or patient groups require additional information as explained below.
Many brand name drugs have cheaper generic drug substitutes that are therapeutically and biochemically equivalent. Prescriptions will also contain instructions on whether the prescriber will allow the pharmacist to substitute a generic version of the drug. This instruction is communicated in a number of ways. In some jurisdictions, the preprinted prescription contains two signature lines: one line has "dispense as written" printed underneath; the other line has "substitution permitted" underneath. Some have a preprinted box "dispense as written" for the prescriber to check off (but this is easily checked off by anyone with access to the prescription). In other jurisdictions, the protocol is for the prescriber to handwrite one of the following phrases: "dispense as written", "DAW", "brand necessary", "do not substitute", "no substitution", "medically necessary", "do not interchange". In Britain's National Health Service, doctors are reminded that money spent on branded rather than generic drugs is consequently not available for more deserving cases.
The dose regimen is the planned schedule for administering a drug to a patient. It specifies the amount of drug given, how often it is administered, and the duration of treatment. The aim is to keep drug levels within the therapeutic range while avoiding adverse effects. A dose regimen typically includes:
Selection of an appropriate dose regimen is important for achieving therapeutic benefit. Incorrect dosing schedules may lead to treatment failure or drug toxicity, especially for medicines with a narrow therapeutic index.
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