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Methimepip
Methimepip
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Methimepip
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Welcome to the community hub built on top of the Methimepip Wikipedia article. Here, you can discuss, collect, and organize anything related to Methimepip. The purpose of the hub is to connect people, fos...
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Methimepip
Methimepip
Names
IUPAC name
4-(1H-imidazol-4-ylmethyl)-1-methylpiperidine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH C500075
UNII
  • InChI=1S/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12) ☒N
    Key: KIAVPENCSGKVQP-UHFFFAOYSA-N ☒N
  • InChI=1/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12)
    Key: KIAVPENCSGKVQP-UHFFFAOYAQ
  • CN1CCC(CC1)CC2=CN=CN2
Properties
C10H17N3
Molar mass 179.262 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Methimepip is a histamine agonist which is highly selective for the H3 subtype. It is the N-methyl derivative of immepip.[1]

References

[edit]
  1. ^ Kitbunnadaj R, Hashimoto T, Poli E, et al. (March 2005). "N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist". Journal of Medicinal Chemistry. 48 (6): 2100–7. doi:10.1021/jm049475h. PMID 15771452.