Michele Pio Pirro (born 5 July 1986) is a motorcycle road racer from Italy, He was 2007 and 2008 the Italian CIV National Champion in the Superstock class and a test rider for Ducati factory racing in MotoGP and rides occasionally as a wildcard.

He has also competed in Grand Prix motorcycle racing and the Supersport World Championship.

Pirro began his Grand Prix career as a wild card in the 2003 Italian Grand Prix in the 125cc class, on an Aprilia motorcycle. After winning the European 125cc Championship in 2004, in 2005 he participated as a full-time rider in the same class with Malaguti, scoring three points in the Chinese Grand Prix and finishing the season in 33rd place. In 2006, he continued to race in the 125 class on an Aprilia – and later a Honda – without scoring points.

In 2007 and 2008, Pirro won the Italian National Championship (CIV) in the Superstock class on a Yamaha YZF-R1.

In 2009, Pirro participated in the Supersport World Championship on a Yamaha, ending in 11th place. In the same year, he won the Italian Supersport Championship. The following year, he switched to Honda and finished in fifth place, with a victory in the Italian round at Imola. He also made a one-off appearance in the Moto2 World Championship at the Aragon Grand Prix, finishing 14th.

Pirro returned to Grand Prix racing in 2011 in Moto2 with Team Gresini. He obtained a victory, in the season finale at Valencia, just two weeks after Gresini's MotoGP rider Marco Simoncelli was killed in a crash at the Malaysian Grand Prix.

Pirro's MotoGP career began in 2012 with Gresini on a FTR motorcycle, with a best placement of fifth at the Valencian Grand Prix, ending the season in 15th place with 43 points.

Since 2013, Pirro has been the official test rider of team Ducati. He has participated in races every year, either as a wildcard entry or as a substitute for injured riders, obtaining his overall best MotoGP result of fourth at the 2018 Valencian season finale.