The Midlands Collegiate Athletic Conference (MCAC) was an intercollegiate athletic conference that competed in National Association of Intercollegiate Athletics. Members of the conference were located in the Midwest United States and were located in Kansas, Missouri, Nebraska, Iowa, Arkansas, and Oklahoma.

Since 1994 when MCAC was established, to the time it dissolved in 2015, the conference only had two commissioners.

The conference has board made up of representatives from the member institutions, and one person from a school is selected as the board's president for two years.

The MCAC had nine full members in the conference's final season, most were private schools:

The MCAC had six other full members during the conference's tenure, most were private schools:

 Full member (non-football) 

The Midlands Collegiate Athletic Conference fielded 11 sports (5 men's and 6 women's), which includes: