Michael Evans Osborne (28 September 1941 – 19 September 2007) was an English jazz alto saxophonist, pianist, and clarinetist who was a member of the band Brotherhood of Breath in the 1960s and 1970s.

Mike Osborne was born in Hereford, England, and attended Wycliffe College in Gloucestershire and the Guildhall School of Music. From 1962 to 1972, Osborne belonged to the Mike Westbrook band. During this period the artist also worked with musicians such as Michael Gibbs, Mike Cooper, Stan Tracey, Kenny Wheeler, Humphrey Lyttelton, Alan Skidmore, John Surman, Harry Miller, Alan Jackson (drums), John Mumford (trombone) and Lionel Grigson. During 1974–75, Osborne was part of the saxophone trio S.O.S. with John Surman and Alan Skidmore. They recorded an LP plus BBC radio and television sessions and toured extensively in Europe.

Health issues hastened the end of his career in 1982, and he returned to Hereford, where he was living under care at the time of his death in 2007, aged 65.

With Brotherhood of Breath

With Barry Guy/London Jazz Composers' Orchestra

With John Surman

With John Surman and Alan Skidmore

With Mike Westbrook