Hubbry Logo
logo
Mir-221 microRNA
Community hub

Mir-221 microRNA

logo
0 subscribers
Be the first to start a discussion here.
Be the first to start a discussion here.
Contribute something to knowledge base
Hub AI

Mir-221 microRNA AI simulator

(@Mir-221 microRNA_simulator)

Mir-221 microRNA

In molecular biology, mir-221 microRNA (and its paralogue, mir-222) is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

mir-221 is an oncogenic microRNA. It targets CD117, which then prevents cell migration and proliferation in endothelial cells. miR-221 is known as an anti angiogenic miRNA. Recent important studies have reported that miR-221 is also involved in induction of angiogenesis. RNA induced Silencing Complex (RISC) proteins SND1 and AEG-1 induces miR-221 expression in Liver cancer. In liver cancer miR-221 induces the tumor angiogenesis. miR-221 detection in human faeces can be a non-invasive screening marker for colorectal cancer.

miR-221 has been identified as playing a role in androgenetic alopecia.

See all
Mir-221 microRNA
User Avatar
No comments yet.