Miss Grand Spain 2018 was the 3rd edition of Miss Grand Spain beauty contest, held at Cerezo Theater, Carmona on 30 June 2018. The contest was won by Mariola Partida Angulo of Sevilla, who was expected to represent Spain at the Miss Grand International 2018 pageant held on 25 October in Myanmar, but later dethroned. The first runner-up, Patricia López of Murcia, was promoted as the replacement.

34 delegates were selected by regional licensees to compete for the national title of Miss Grand Spain 2018.