Mitchell Gale (born January 7, 1990) is an American former professional football quarterback who played in the Canadian Football League (CFL). He played college football at Abilene Christian University. He was a member of the Toronto Argonauts, Hamilton Tiger-Cats, Saskatchewan Roughriders, Calgary Stampeders, BC Lions, and Winnipeg Blue Bombers of the CFL.

Gale attended Alva High School in Alva, Oklahoma.

Gale was a four-year starter at Abilene Christian University. He threw for 97 touchdowns and over 12,000 career yards. Gale and former ACU quarterback Billy Malone became just the third pair of teammates to throw for over 12,000 yards.

Gale attended rookie mini-camp with the St. Louis Rams of the National Football League in May 2013 on a tryout basis.

Gale was signed by the Toronto Argonauts on May 16, 2013. He was released by the Argonauts on September 2, 2015.

Gale signed with the Hamilton Tiger-Cats on November 3, 2015.

Gale was signed by the Argonauts on June 10, 2016.

On July 2, 2016, Gale and Matt Sewell were traded to the Saskatchewan Roughriders for Shawn Lemon and a conditional 2018 CFL draft pick. In Week 4 starting quarterback Darian Durant left the game in the early second quarter, thrusting Mitchell Gale into the starting role. Gale made his first career CFL start on July 22, throwing for 354 yards and one touchdown in a come-from-behind victory at home over the Ottawa Redblacks, which was the Roughriders' first win of the 2016 campaign. Gale would also start the following week before Durant returned from his leg injury. Having been eliminated from playoff contention the Riders started Gale at quarterback for the final week of the season. He finished the season having completed 79 out of 137 pass attempts (58%) for 937 yards with 2 touchdowns and 3 interceptions. On January 27, 2017, about two weeks before becoming a free agent, Gale was released by the Riders along with three of his teammates.