Mohammad Daoud Khan, (18 July 1909 – 28 April 1978), also romanized as Daud Khan or Dawood Khan, was an Afghan military officer and politician who served as prime minister of Afghanistan from 1953 to 1963 and, as leader of the 1973 Afghan coup d'état which overthrew the monarchy, served as the first president of Afghanistan from 1973 until his assassination in 1978.

Born into the Afghan royal family and addressed by the prefix "Sardar", Khan started as a provincial governor and later a military officer before being appointed as prime minister by his cousin, King Mohammad Zahir Shah, serving for a decade. Having failed to persuade the King to implement a one-party system, Khan overthrew the monarchy in a virtually bloodless coup with the backing of Afghan Army officers, and proclaimed himself the first president of the Republic of Afghanistan, establishing an autocratic one-party system under his National Revolutionary Party.

Khan was known for his autocratic rule, and for his educational and progressive social reforms. Under his regime, he headed a purge of communists in the government, and many of his policies also displeased religious conservatives and liberals who were in favor of restoring the multiparty system that existed under the monarchy. Social and economic reforms implemented under his ruling were successful, but his foreign policy led to tense relations with neighboring countries. In 1978, he was deposed and assassinated during the 1978 Afghan coup d'état, led by the Afghan military and the communist People's Democratic Party of Afghanistan (PDPA). His body was discovered 30 years later and was identified by a small golden Quran gifted by King Khalid of Saudi Arabia he always carried. He received a state funeral.

Mohammad Daoud Khan was born in Kabul, Emirate of Afghanistan, into a Barakzai Pashtun family and was the eldest son of the diplomat Prince Mohammad Aziz Khan (1877–1933; an older half-brother of King Mohammad Nadir Shah) and his wife, Khurshid Begum. His father was assassinated in 1933 in Berlin, while serving as the Afghan Ambassador to Germany. He and his brother Prince Naim Khan (1911–1978) then came under the tutelage of their uncle Mohammad Hashim Khan (1884–1953). Daoud proved to be an apt student of politics.

Educated in France, he served as a senior administrator in the Kingdom of Afghanistan, serving as Governor of the Eastern Province in 1934–35 and in 1938–39, and was Governor of Kandahar Province from 1935 to 1938.

In 1939, Khan was promoted to Commander of the Central Forces. As commander, he led Afghan forces against the Safi during the Afghan tribal revolts of 1944–1947, and thereby came to national attention. Daoud's military victories contributed to his rise to power, including his later assumption of the office of prime minister.

From 1946 to 1948, he served as Defense Minister, then Interior Minister from 1949 to 1951. In 1948, he served as Afghan Ambassador to France.

In 1951, he was promoted to General and served in that capacity as Commander of the Central Corps of the Afghan Armed Forces in Kabul from 1951 to 1953.