Mrs. Doubtfire is a 1993 American comedy-drama film directed by Chris Columbus, written by Randi Mayem Singer and Leslie Dixon, based on the 1987 novel Madame Doubtfire, by Anne Fine. The film was produced by Mark Radcliffe, Marsha Garces Williams and her then-husband Robin Williams, who also starred in the lead role. The film co-stars Sally Field, Pierce Brosnan, Harvey Fierstein, and Robert Prosky. It follows a recently divorced voice actor who disguises himself as an elderly female housekeeper in order to spend time with his children.

Mrs. Doubtfire was released in the United States by 20th Century Fox on November 24, 1993. It grossed $441.3 million on a $25 million budget, making it the second-highest-grossing film of 1993. While critical reception was mixed, the film won the Academy Award for Best Makeup, and the Golden Globe Award for Best Motion Picture – Musical or Comedy. Williams was awarded the Golden Globe Award for Best Actor in a Motion Picture – Musical or Comedy.

Freelance voice actor Daniel Hillard lives in San Francisco and is a loving and devoted father to his three children - fourteen-year-old Lydia, twelve-year-old Chris, and five-year-old Natalie - though his workaholic wife Miranda considers him immature and unreliable. After quitting a gig following a disagreement over a morally questionable script, Daniel returns home to throw Chris a chaotic birthday party, despite Miranda's objections due to Chris's poor grades. Miranda arrives home from work early to break up the party after receiving a noise complaint from neighbor Gloria; in the ensuing argument, she tells Daniel she wants a divorce. Due to Daniel's unemployed and homeless status, Miranda is granted sole custody of the children, with Daniel having visitation rights every Saturday; shared custody is contingent on Daniel finding a steady job and suitable residence within three months.

Daniel secures an apartment and a job as a shipping clerk at a television station. After learning that Miranda is looking to hire a housekeeper, Daniel secretly alters her classified ad form and calls her using his voice acting skills to pose as various undesirable applicants before calling as "Euphegenia Doubtfire" (a name he derives from a newspaper headline), an elderly British nanny with strong credentials. Impressed, Miranda invites Mrs. Doubtfire for an interview. Daniel's brother, Frank, a makeup artist, and Frank's domestic partner, Jack, use makeup and prosthetics to help Daniel appear as an old lady.

Miranda hires Mrs. Doubtfire following a successful interview. The children initially struggle under her authority, but eventually come around and thrive, while Miranda becomes more easygoing and closer with the kids. Daniel also further improves himself by becoming more responsible and learning several household skills, earning Miranda's respect. However, Miranda puts more trust in Mrs. Doubtfire than in Daniel, and cannot bring herself to dismiss her. Miranda also begins dating an old friend, Stu Dunmeyer, to Daniel's chagrin. One evening, Chris discovers Mrs. Doubtfire standing while urinating and frantically instructs Lydia to call the police. Daniel reveals the truth to the two, and they agree to keep his secret so that they can continue spending time with him.

One day, the station's CEO, Jonathan Lundy, sees Daniel playing with props on the set of a recently canceled children's show. Impressed by his voice acting, humor, and imagination, Lundy invites Daniel to dinner to discuss plans for a new show. The meeting turns out to be at the same place and time as a planned birthday dinner for Miranda, to which Mrs. Doubtfire is invited. Daniel spends the night changing in and out of the Mrs. Doubtfire costume to attend both events. Becoming intoxicated, Daniel accidentally returns to Lundy in costume, but explains himself by claiming Mrs. Doubtfire is his idea for the new show's host. After learning of Stu's pepper allergy, Daniel sneaks into the kitchen and seasons Stu's jambalaya with powdered cayenne. When Stu begins choking, a regretful Daniel administers the Heimlich maneuver, which causes the prosthetic mask to slip off and expose his identity. Horrified, Miranda leaves with the kids.

At their next custody hearing, Daniel points out that he has met the judge's requirements ahead of schedule, then explains that his actions were done out of love for his children and begs to still be allowed to see them. The judge dismisses Daniel's words as another ruse, grants Miranda full custody of the kids, and further restricts Daniel's rights to supervised Saturday visits. This devastates Daniel, the children, and even Miranda, who realizes her resentment of Daniel has been hurting the whole family. Without Mrs. Doubtfire, Miranda and the kids become miserable, acknowledging how much "she" improved their lives. They then discover that Daniel, as Mrs. Doubtfire, is hosting the new children's show Euphegenia's House, which becomes a nationwide hit.

Miranda visits Daniel on set and admits that things were better when he was involved with the family. She arranges joint custody, allowing Daniel to take the kids daily after school. As Daniel leaves with the kids, Miranda watches an episode of Euphegenia's House in which Mrs. Doubtfire answers a letter from a young girl whose parents recently separated. Mrs. Doubtfire assures the girl that no matter what arrangements families have, love will prevail.