Mulholland Books (US) is an imprint of Little, Brown and Company, a division of the Hachette Book Group. It specializes in publishing mysteries, thrillers, and suspense novels.

Little, Brown and Company announced the creation of Mulholland Books on June 15, 2010. Mulholland Books is named after Mulholland Drive, a winding stretch of road that follows the ridge line of the Hollywood Hills. The imprint launched in Spring 2011 with the publication of a book by Marcia Clark.

For a time writer and producer Derek Haas curated a series of short stories on the Mulholland Books website under the title "Popcorn Fiction".