Multilateral foreign policy of the Holy See

The multilateral foreign policy of the Holy See is particularly active on some issues, such as human rights, disarmament, and economic and social development, which are dealt with in international fora.

Both at the United Nations and at the various international conferences, the Holy See has promoted the "Culture of life", opposing efforts to legalize or endorse abortion and euthanasia through internationally legally binding instruments or non-binding declarations, advocating for the abolition of death penalty at the global level, and seeking to ban research on human embryos. At the United Nations General Assembly, the Holy See stated that:

The right to life and respect for human dignity remains an inalienable right of every person and a founding principle of this Organization. It is therefore the duty of States to promote and protect this right from conception until natural death. To that end, we must work consistently to reverse the culture of death embraced by some social and legal structures which justify certain forms of destruction of life as a legal necessity or a medical service.

At the international level, the Holy See has underlined the ethical problems raised by some current forms of biomedical research. The Holy See has been particularly active in the area of human cloning. In 2001, when Germany and France proposed at the United Nations General Assembly the adoption of an international convention to ban reproductive human cloning, the Holy See, together with a coalition of like-minded states that included Spain, Philippines, the United States, and Costa Rica, noted that such a convention would implicitly legitimize the cloning of human beings for research purposes, which is more serious from an ethical point of view than the reproductive one, and proposed banning all forms of human cloning. The Holy See objected to the "production of millions of human embryos with the intention of destroying them as part of the process of using them for scientific research" and to the instrumentalization and victimization of women, specially of the poorest women, in the process of harvesting the necessary human eggs. These efforts lead to the successful adoption, in March 2005, of a United Nations Declaration on Human Cloning, which calls upon all member states of the UN "to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life".

In 2007, the Holy See argued at the United Nations that the death penalty should be used exceptionally, only when its use is necessary to protect society against an aggressor, a situation which is "practically non-existent" today, since societies have other ways of protecting their citizens. In addition, it noted that capital punishment is frequently discriminatory, since it is imposed most often on the poorest and on members of religious, ethnic and racial minorities; and that it is irreversible, since it excludes all possibilities of recourse and restoration in the event of a miscarriage of justice. Consequently, the Holy See worked for the adoption of a UN moratorium on the death penalty.

Following Vatican Council II, the Holy See has uphold, at the international level, the centrality of the freedom of conscience and religion among all Human Rights since, in its view, those freedoms impinge on essence of the Human person. Pope Benedict XVI noted that "religious freedom expresses what is unique about the human person, for it allows us to direct our personal and social life to God, in whose light the identity, meaning and purpose of the person are fully understood. To deny or arbitrarily restrict this freedom is to foster a reductive vision of the human person; to eclipse the public role of religion is to create a society which is unjust, inasmuch as it fails to take account of the true nature of the human person; it is to stifle the growth of the authentic and lasting peace of the whole human family." Thus, the respect for freedom of religion is at the basis of the respect for all other human rights. Consequently, the Holy See has called upon States to comply with their international commitments to respect those rights. It has stated:

Recognition of the dignity of each and every person, which the Human Rights Council was formed to protect and promote, entails full respect for the inner and transcendent dimension of the human person, which is an integral part of what it means to be a human being. Through the free exercise of conscience and moral decision making, human beings are able to transform themselves into living members of social life whose good will, charity and hope promote the dignity and wellbeing of every member of the human family. Intrinsically linked to freedom of conscience is the freedom of religion by which human beings are able to pursue the most important relationship of their life, that is, their relationship with God. Freedom of religion necessarily entails the freedom to ascribe to a set of beliefs, to adopt or change one’s religion, to profess one’s faith and to practice fully that faith openly and publicly. Governments have a solemn responsibility to safeguard rather than ridicule this inalienable right. Since the State is not the author of any fundamental human right, it must respect that intimate and fundamental sanctuary of human freedom, the conscience, and to allow each conscience its fullest and highest expression in the free exercise of religious faith.

In parallel, the Holy See condemns the violation to the freedom of religion, specially when suffered by Christians: