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Munc-13

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Munc-13

Munc-13 (an acronym for mammalian uncoordinated-13) is a protein which complexes with RIM and likely comprises part of cellular structure which anchors synaptic vesicles. In human this protein is coded by the UNC13A and UNC13B genes. Its activation by DAG seems to be important for maintaining high rate of synaptic release during prolonged repetitive stimulation.

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