The Munduruku, also known as Mundurucu or Wuy Jugu, are an indigenous people of Brazil living in the Amazon River basin. Some Munduruku communities are part of the Coatá-Laranjal Indigenous Land. They had an estimated population in 2014 of 13,755.

Traditionally the Munduruku's territory, called Mundurukânia in the 19th century, was the Tapajós river valley. In 1788, they completely defeated their ancient enemies the Muras. After 1803 they lived at peace with the Brazilians.

The Munduruku live in southwest of the state of Pará along the Tapajós river and its tributaries in the municipalities of Santarém, Itaituba and Jacareacanga, in the east of the state of Amazonas along the Canumã River in the municipality of Nova Olinda and the municipality of Borba, and in the north of the state of Mato Grosso in the Peixe River region in the municipality of Juara. They usually inhabit forest regions on the margins of navigable rivers, and their traditional villages are in "Tapajós fields", patches of savannah within the Amazon rainforest. The largest numbers live in the Munduruku Indigenous Territory, with most of the villages along the Cururu River, a tributary of the Tapajós.

Today the Munduruku face threats to their homelands from the dams of the Tapajós hydroelectric complex, illegal gold-panning, and a new waterway construction on the Tapajós River. The reservoir of the proposed Chacorão Dam on the Tapajós river would flood 18,700 hectares (46,000 acres) of the Munduruku Indigenous Territory. The reservoir of the proposed São Luiz do Tapajós Dam on the Tapajós would flood about 7% of the Sawré Muybu Indigenous Territory.

Also known as the Mundurucu, Maytapu, and Cara Preta, the Munduruku call themselves Wuy Jugu. Oral history says the name Munduruku comes from their enemies the Parintintin people and means ‘red ants’, based on the historical Munduruku tactic of attacking en masse.

The Munduruku have a distinctive residence pattern. Rather than a pattern based on conjugal or affinal bonds, in Munduruku villages all males over the age of thirteen live in one household and all the females live with all of the males under thirteen in another.^{[citation needed]}.

Before the discovery of America by Columbus, a tribal ritual was practised by the Munduruku consisting of removing the skin from a man’s head and then drying it. The result was a smaller head used for religion purposes. This tribal practice is no longer carried out but many "smaller heads" can still be seen in museums all over the world.

The Munduruku language is part of the Tupi language family.