Myra McQueen is a fictional character from the British Channel 4 soap opera Hollyoaks, played by Nicole Barber-Lane. She made her first screen appearance during episode 1796, originally broadcast on 12 June 2006 and was introduced by producer Bryan Kirkwood as part of the McQueen family. The character is initially designed to play a supporting role in her family's stories. She is characterised as a no-nonsense matriarch who is "fiercely protective" of her family and puts her children first. Myra has a series of failed relationship, leading to her many children. One of her early stories introduces Niall Rafferty (Barry Sloane), Myra's abandoned son who returns for revenge on his mother. The story concludes in a stunt when Niall explodes a church, killing Myra's daughter Tina Reilly (Leah Hackett). Barber-Lane left the soap in 2013 and Myra fakes her death after being shot.

Having made a brief return in January 2014, the character was reintroduced in September 2014 as part of ongoing family stories. Barber-Lane took a break in early 2015, returning in October 2015. Writers created a love interest for Myra in the form of Diego Salvador Martinez Hernandez De La Cruz (Juan Pablo Yepez). Their relationship was used to provide lighter, comedic stories and counterbalance the show's darker plots. It was then challenged through cheating accusations and Diego's family, before ending when Diego cheats. As part of the story, Myra becomes pregnant with her eighth child.

In 2016, producers explored the character's backstory through the introduction of Sally St. Claire (Annie Wallace), a trans woman who fathered Myra's son, John Paul McQueen (James Sutton), before her transition. Initially portrayed as feuding, the pair develop a friendship before being romantically paired together. Writers also used the character as part of a comedic friendship with Marnie Nightingale (Lysette Anthony), which won an award. Barber-Lane departed the cast again in 2019 and Myra leaves following the breakdown of her relationship with Sally. Barber-Lane returned for a guest stint in January 2024, before returning for intermittent appearances from December 2024. The character has received a positive response from viewers and critics alike.

In 2006, executive producer Bryan Kirkwood created Myra McQueen as the matriarch of the McQueen family, who were described as Kirkwood's "brainchild". Actress Nicole Barber-Lane was cast in the role and she was initially informed that the character was a middle class beauty therapist and business owner with a mechanic husband and multiple children. The character was reimagined as a "rough" single mother to multiple children with writers drawing inspiration from reality television star Lizzy Bardsley. Barber-Lane learnt this on her first day when she visited the costume department.

Hollyoaks' executive producer Lucy Allan said that Myra is not central to storylines as she is not central to the show. She explained that Myra plays a very important role as the mother in the McQueen household, but that she would find it "abnormal" to run a storyline from Myra's perspective. After Barber-Lane lost weight she was asked to put on weight by producers as she "didn't look like Myra any more".

Meet Myra McQueen, the mummy bear of Hollyoaks. Enjoying domestic chaos, she's fiercely protective of her family (even when they're in the wrong) and keeps them in line with a mixture of love, understanding and bacon sarnies – all three of which have been in great demand during her Hollyoaks reign, which spans divorce, murder, adultery and a long lost (and very angry about it) son!

— An excerpt from Myra's profile on the official Hollyoaks website.

Myra is characterised as the protective matriarch of the McQueen family who cares deeply about each family member. A journalist from the Hollyoaks website wrote that Myra possesses scepticism, scathing remarks and relentless double standards. They described Myra as the "queen of the McQueen clan", saying she is the "mediator of squabbling kids, harbourer of stray relatives, she is the rock which grounds the feral McQueen family through turmoils and tragedies galore". They continued that Myra has a "feisty, no-nonsense nature" before saying that "with her trademark gold chains and sovereigns, we'd put our money on Myra over Mr. T any day". Myra is portrayed as a loyal Catholic, something she shares with her daughter Carmel McQueen (Gemma Merna). Her backstory states that she has had many failed relationships, resulting in several children. Myra is a single mother and raised all of her children alone. Hollyoaks' international broadcaster, BBC America, noted that this provided the character with "a survival instinct that she's instilled in her children." They described Myra as "loud, sexually free and ready to attack to protect the ones she loves", which was reflected in the characterisation of her eldest children, Jacqui McQueen (Claire Cooper) and Mercedes McQueen (Jennifer Metcalfe). On Myra's parenting technique, Barber-Lane said: "I think like many mothers, she tries her best. Whether her best is up to scratch is another question. She's certainly a very lenient parent, but also she would do anything for her kids, that comes before anything else". Cooper thought that although Jacqui often adopts a maternal approach in the McQueen family, Myra is always "the boss" in the family. She added that both characters possess a "matriarch feel" and if the family had to face a big problem, then Myra would be the one to deal with it rather than Jacqui. Barber-Lane related to Myra personally as a mother, dubbing her a "lioness and protector".