Nathan Barley is a British Channel 4 television sitcom written by Charlie Brooker and Chris Morris, directed by Morris and starring Nicholas Burns, Julian Barratt, Claire Keelan, Richard Ayoade, Ben Whishaw, Rhys Thomas and Charlie Condou. The series of six weekly episodes began broadcasting on 11 February 2005 on Channel 4. Described by his creator as a "meaningless strutting cadaver-in-waiting", the character originated on Brooker's TVGoHome – a website parodying television listings – as the focus of a fly-on-the-wall documentary called Cunt.

Nathan Barley, played by Nicholas Burns, is a webmaster, guerrilla filmmaker, screenwriter, DJ and in his own words, a "self-facilitating media node". Whilst desperate to convince himself and others that he is the epitome of urban cool, Nathan is secretly terrified he might not be, which is why he reads Sugar Ape magazine, his bible of cool. Sugar Ape has been described as a spoof of Dazed & Confused and Vice, although Brooker has stated that "the Sugar Ape "Vice" issue from Ep5 wasn't an assault on Vice magazine – I think it just (understandably) ended up looking that way".

The website consists of pranks caught on camera, artwork which clumsily satirises contemporary politics, photos of him with attractive women and famous figures (some of them digitally edited to insert himself), and photos of him standing on street corners in major cities around the world.

The humour derives from the rapid rise of both the Internet and digital media, and the assumption by publishers and broadcasters that almost any such work is worthy of attention. Barley and his peers are often hired ahead of actual journalists and talented writers trying to make intelligent points, such as the earnest documentary filmmaker Claire Ashcroft (Claire Keelan), and her brother Dan (Julian Barratt), the series' two other central characters. Claire seeks to highlight the plight of the inner city's homeless and drug-dependent; Dan is a jaded, opinionated and apathetic hack who, having written an article for Sugar Ape entitled "The Rise of the Idiots", is appalled to find that "the idiots" in question – Nathan and his contemporaries – have adopted him as their spiritual leader, failing to see that they are the very people he was criticising.

While Dan sees a clear distinction between himself and the "idiots", he's frequently forced to compromise his own ethics in order to earn a living, and seems to be fighting the dawning realisation that he may actually be the very thing he despises. At the same time, Claire, who clearly wants to see herself as socially responsible and philanthropic, is doggedly determined to further her own career.

Other recurring characters include Nathan's idiot flatmate Toby (Rhys Thomas) and the staff at Dan Ashcroft's magazine, Sugar Ape: asinine chief editor Jonatton Yeah? (Charlie Condou), Ned Smanks (Richard Ayoade) and Rufus Onslatt (Spencer Brown), a pair of gormless graphic designers, and receptionist Sasha (Nina Sosanya). Barley has an inoffensive young assistant called Pingu (Ben Whishaw). The eccentric and ludicrous Doug Rocket, founder member of The Veryphonics, and played by comedian David Hoyle (a spoof of Dave Stewart of Eurythmics), also appears in several episodes.

Dan Ashcroft's flatmate is a DJ called "Jones", who appears blissfully unaware of the antisocial cacophony he creates. Jones is played by Noel Fielding, Barratt's partner in comic duo the Mighty Boosh.

The working title for the series was Box of Slice.