Milli released an extended play with five versions of the song on December 24, 2023. It has Bryson Tiller, the original, sped up and slowed down, and a Lil Yachty feature.[7][8] According to HotNewHipHop, "Never Lose Me" is a quick two-minute track that paints a story of Milli doing all she can to not lose this successful man.[9] On January 19, 2024, a string of messages from SZA were revealed by Flo Milli. Social media users were speculating that SZA offered to sing on Flo Milli's song "Never Lose Me" after exchanging text messages. SZA shared Flo Milli's song on her Instagram account to heighten the anticipation alongside a photo from the studio showing a Digital Audio Workstation.[10][11] Flo Milli performed "Never Lose Me" at Genius Open Mic studio.[12] According to Billboard Magazine, "Never Lose Me" is the biggest hit of Flo Milli's career.[13]
On March 14, 2024, Flo Milli announced a remix of "Never Lose Me" with SZA and Cardi B which was released the following day, 15, March 2024 alongside the album Fine Ho, Stay.[14]
[15]
"Never Lose Me" received widespread attention on TikTok, being played in over 135,000 TikTok clips. It reached number 17 on the Billboard Rap Airplay chart and number 18 on the Hot R&B/Hip-Hop Songs chart. It debuted at number 84 and peaked at number 15 on the Billboard Hot 100 chart, becoming her first entry on the chart.[4][16][17] "Never Lose Me" has the longest running streak at No. 1 on the TikTok Billboard Top 50 of any song since its release in September 2023,[18] having spent four weeks straight at the top charts.[19][20] The song also entered Top 10 on Hot R&B/Hip-Hop Songs.[21]
On December 18, 2023, Flo Milli released the music video for "Never Lose Me". It was directed by Boni Mata and Leff. Flo Milli was fully clothed in Pucci for the visuals, which was taken at five in the morning in Houston to portray nightlife.[22][23]