Omloop Het Nieuwsblad, previously Omloop Het Volk, is a one-day road cycling race in Belgium, held annually in late February. It is the opening event of the Belgian cycling season, as well as the first race of the year in Northwestern Europe, and holds significant prestige because of it. Since 2017, the race has been part of the UCI World Tour, cycling's top-tier professional events.

The race starts in Ghent, Flanders, and finishes in Ninove, Flanders. The race route covers the hills in the Flemish Ardennes, marking the start of the cobbled classics season in Europe. Due to its early calendar date, it is characterized by often cold weather, coming as a contrast to the early-season stage races in the Middle East and Southern Europe. The day after the Omloop, Kuurne–Brussels–Kuurne completes the opening weekend. The race is named after the newspaper sponsoring the event – Het Volk from 1947 to 2009, and Het Nieuwsblad from 2009 to present.

Since 1950, Omloop Het Nieuwsblad U23, a race for under-23 men, has been held on the same day as the men's race.

Since 2006, a women's edition of Omloop Het Nieuwsblad is held on the same day as the men's race, also starting in Ghent and finishing in Ninove, approximately 130 kilometres in distance. Both events are organized by Flanders Classics. Since 2023, the race is part of the UCI Women's World Tour.

First held in 1945, the race was called Omloop van Vlaanderen ("Circuit of Flanders"). The event was initiated by Flemish newspaper Het Volk, in response to rivaling newspaper Het Nieuwsblad's classic, the Tour of Flanders. Het Volk, of left-leaning publication, wanted to start a new cycling event in Flanders as a rival race to what it saw as the Tour of Flanders' closeness to the Nazis during World War II. The Ronde's organizers protested that the name was too close to their own – there is little semantic difference between "Ronde" and "Omloop". The Belgian cycling federation demanded Het Volk to change the name of the event, prompting Het Volk to serve as title sponsor of their own race.

In 2009 the former rival newspapers Het Volk and Het Nieuwsblad merged, causing the event to be renamed Omloop Het Nieuwsblad for its 64th edition. Since 2010, the race has been organised by Flanders Classics. Until 2016, Omloop Het Nieuwsblad was ranked as a 1.HC event of the UCI Europe Tour; since 2017, it is included in the UCI World Tour.

Due to its early-season calendar date, the race has occasionally been affected by cold and wintry conditions, with three editions of the event having been cancelled. The 1971 race was postponed due to snow and run three weeks later. In 1986 and 2004 organizers were forced to cancel the race, as snow and freezing temperatures had made the route too dangerous and riders' safety could not be guaranteed. In modern times, organizers rely heavily on weather forecasts and adjust the course if some sectors are deemed unsafe. Unrelated to the weather, the 1960 race was cancelled following a disagreement between the organizers and cycling's ruling body UCI.

Traditionally the opening event of the Belgian cycling season, the race holds particular importance for Belgian cyclists. Throughout its history, Belgian riders, comfortable with cold weather and aided by large, supportive crowds, have dominated the race. Belgians have won 56 editions, although, exemplary for the growing international status of the race, they have only won four of the last ten editions. In 1948 Italian cycling icon Fausto Coppi won the race, but was disqualified for receiving an illegal wheel-change.