Open House Melbourne (OHM) is an event held in Melbourne, Victoria, Australia, that showcases many of the city's buildings to the public. This annual event has been held on the last weekend in July since 2008.

Open House Melbourne is also a not-for-profit association that runs the Open House Weekend, as well as an annual program of events.

Open House Melbourne is an initiative of the Committee for Melbourne Future Focus Group. The inaugural Open House Melbourne 2008 event saw eight buildings open and more than 30,000 visits across the day. Since then, the event has grown and the 2010 event expanded to 59 buildings, incorporating Docklands in addition to Melbourne's CBD, and attracted almost 65,000 visitors.

In the 2011 event 75 buildings opened their doors and attracted 100,000 visitors.

For its fifth year, the 2012 event featured 100 buildings and attracted 135,000 visitors.

In the 2013 event 111 buildings opened over the weekend and attracted 130,000 visitors.

The 2016 event featured over 100 buildings.

In 2017 Open House Melbourne held the Open House Ballarat Weekend, the first regional program run by Open House Melbourne, in partnership with City of Ballarat and Visit Ballarat. In 2018 and 2019 the organisation also held Open House Bendigo in partnership with The City of Greater Bendigo.