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Orphan virus

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Orphan virus

An orphan virus is a virus that is not associated with a disease but may possess pathogenicity.

Gilbert Dalldorf, a pathologist who showed that Coxsackie viruses paralyze mice but not humans, indicated that the term ‘orphan’ was created "in a moment of conviviality" by a group of virologists.

Many enteroviruses are referred to as ECHO, enteric cytopathic human orphan viruses, because they were originally not associated with any disease.

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