Laura F. Osborn High School, also known as Osborn Academy of Mathematics is a public high school in the Detroit Public Schools Community District (DPSCD), located in Northeast Detroit.

Currently, the school has over 20 course offerings.

In 2010 Mildred Gaddis of WCHB stated that Osborn "is considered the glue to the community."

Laura F. Osborn High School was opened in February 1957. It was named after Laura Freele Osborn, the first female president of the Detroit Board of Education. When opened it had no auditorium, gym or pool, no facilities for vocational courses such as automotive. It took the Board of Education over four years to develop these, although the funds had been appropriated before January 1957. On the northwest side, Osborn's 'sister' school, Henry Ford had these facilities built by the end of 1959. Parents of Osborn students inquired and made visits to the Board offices and never received positive answers regarding the delay. The first student newspaper was called The Lance, the masthead designed by Gregg T. Trendowski (Class of June 1960). The teams were named the Knights, a name suggested by Gregg Trendowski (a member of the first student council and member of a special committee for name selections). Mr. Trendowski also designed the team logos and the yearbook (The Acolyte) logo in February 1957.^{[citation needed]}

In 2006 Kimberly Chou of The Michigan Daily said that the school was "often criticized for its lack of resources and tension among students."

The school complex was divided into three separate schools occupying the same campus in 2009.

In 2010 Robert Bobb, the emergency financial manager of the school district, announced that Osborn was closing. In July 2010 Osborn High School was closed; it reopened in August of that year. DPS officials planned to keep the facility open for two years.

An April 2011 report from the office of Mayor of Detroit Dave Bing stated that gangs have caused problems at Osborn High.