Protein Jade-3 is a protein that in humans is encoded by the PHF16 gene.

This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.