Pet Shop of Horrors is a Japanese manga series written and illustrated by Matsuri Akino. It was serialized in Ohzora Publishing's Apple Mystery, and later in Bunkasha [ja]'s Horror M from 1994 to 1998, with its chapters collected in ten tankōbon volumes. The series focuses on the eccentric Count D, proprietor of a mysterious pet shop located in the heart of Chinatown, and the numerous patrons who visit his supernatural shop. The series was licensed in North America by Tokyopop.

A four-episode anime television series produced by Madhouse was broadcast in 1999. A second manga series, titled Pet Shop of Horrors: Tokyo (known as New Petshop of Horrors in Japan) was serialized by Asahi Sonorama (and later Asahi Shimbun Publications) in Mungekan [ja] from 2004 to 2009, and later published as a webcomic on Yahoo! Comics [ja]'s Horror & Fantasy Club site from 2009 to 2012. Its chapters were collected in twelve volumes. The manga was also licensed in North America by Tokyopop, who only released eight volume from 2008 to 2011.

A spin-off series, titled Pet Shop of Horrors: Passage-hen, which follows Count D's grandfather in Fin de siècle Paris, was irregularly published in HarperCollins Japan's Mugentō (2013) and Harlequin Original (2015–2017); five volumes were released. Another spin-off, titled Petshop of Horrors: Hyōhaku no Hakobune-hen, featuring Count D's father as the protagonist, was serialized in Harlequin Original from 2018 to 2020, with its chapters collected in three volumes.

"Count D" is the mysterious caretaker of a pet shop in Los Angeles Chinatown. Each of D's rare pets, which all have strangely humanoid appearances, comes with a contract with three major points. These points differ for each animal sold (although each animal's contract includes not showing it to anyone), and breaking this contract usually results in dire (and sometimes disturbing) consequences for the buyer, for which the pet shop claims no liability.

Individual chapters of Pet Shop of Horrors are often based on these consequences, and are each written as a stand-alone story, usually introducing one or more new characters in each chapter. With the exception of the main characters and their families, it is rare for a character to carry over to a later chapter, providing the series with a very episodic nature.

The detective Leon Orcot is used to tie the chapters together into an ongoing plot, usually in the form of a subplot within each chapter. Initially he suspects D of malicious criminal activity and using the pet shop as a front for drug trafficking. As the series progresses, he learns more about the pet shop and D himself, entering into a strange friendship of sorts with D as he works to uncover the truth.

Written and illustrated by Matsuri Akino, Pet Shop of Horrors was serialized in Ohzora Publishing's Apple Mystery (November 1994 to July 1998 issues), and later in Bunkasha [ja]'s Horror M (in 1998). Ohzora Publishing released ten tankōbon volumes, under the Missy Comics DX imprint, from March 1995 to September 1998. Bunkasha later released the series in four volumes from February 24 to March 29, 1999.

In North America, the manga was licensed for English release by Tokyopop. The ten volumes were released from June 17, 2003, to January 11, 2005. In August 2024, Seven Seas Entertainment announced that it had licensed the series and it will be released in a collector's edition with an all-new translation starting in February 2025. It was distributed in New Zealand and Australia by Madman Entertainment.