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| Pituitary disease | |
|---|---|
 | |
| Pituitary | |
| Specialty | Endocrinology  |
A pituitary disease is a disorder primarily affecting the pituitary gland.[1]
The main disorders involving the pituitary gland are:
| Condition | Direction | Hormone |
|---|---|---|
| Acromegaly | overproduction | growth hormone |
| Gigantism | overproduction | growth hormone |
| Cushing's disease | overproduction | adrenocorticotropic hormone |
| Growth hormone deficiency | underproduction | growth hormone |
| Syndrome of inappropriate antidiuretic hormone | overproduction | vasopressin |
| Diabetes insipidus (can also be nephrogenic) |
underproduction | vasopressin |
| Sheehan syndrome | underproduction | any pituitary hormone |
| Pickardt-Fahlbusch Syndrome | underproduction | any pituitary hormone, except prolactin, which is increased |
| Hyperpituitarism (most commonly pituitary adenoma) | overproduction | any pituitary hormone |
| Hypopituitarism | underproduction | any pituitary hormone |
Overproduction or underproduction of a pituitary hormone will affect the respective end-organ. For example, insufficient production (hyposecretion) of thyroid stimulating hormone (TSH) in the pituitary gland will cause hypothyroidism, while overproduction (hypersecretion) of TSH will cause hyperthyroidism. Thyroidisms caused by the pituitary gland are less common though, accounting for less than 10% of all hypothyroidism cases and much less than 1% of hyperthyroidism cases.[2][3]
| Authority control databases: National |
|---|
