Polog (Macedonian: Полог, romanized: Polog; Albanian: Pollog), also known as the Polog Valley (Macedonian: Полошка Котлина, romanized: Pološka Kotlina; Albanian: Lugina e Pollogut) is located in the north-western part of North Macedonia, near the border with Kosovo.

It is divided into Upper Polog (Macedonian: Горен Полог; Albanian: Pollogu i Epërm) and Lower Polog (Macedonian: Долен Полог; Albanian: Pollogu i Poshtëm). Tetovo and Gostivar are the largest populated towns in this valley and Albanians form an ethnic majority in the region.

Polog Statistical Region is named after the valley.

The name Polog (Cyrillic: Полог) is Slavic in origin, most likely coming from the Slavic word pole (Cyrillic: поле) meaning "field".

The Polog Valley and the surrounding regions belonged to the Illyro-Dardanian cultural sphere of influence. Throughout antiquity, the Polog valley and its main settlements - Oaeneum and Draudacum - were ruled and inhabited by the Illyrian Penestae tribe as well as the Dardanians. The Polog region served as a border region between the Dardanians and the lands of the Paeonians. In the period of 800–550 BC, the Dardani broke into Pelagonia via Oaeneum (Tetova) and Draudacum (Gostivar) and pushed the Phrygian Bridges there into the northern hills.

During the Roman conquests of the Balkans, the Illyrian king Gentius was allied with the Romans against the Ancient Macedonians in 171 BCE. By 170 BCE, the Illyrians and the Romans, led by Appius Claudius, were on the verge of victory. However, Gentius changed sides in 169 BCE and allied himself with Perseus of Macedon, leading his army to a victory over the Romans in Uskana by way of Oaeneum in the Polog region. In 169 BCE, Oaeneum was conquered by the Romans, whom the Penestae were generally allied with. After the conquest of Uskana, Perseus of Macedon captured Draudacum and Oaeneum, thereby subduing the Polog region temporarily. However, by 168 BCE, Gentius and Perseus were both defeated by the Romans and the Polog Valley region became a part of the Roman province of Illyricum.

The Polog region remained within Illyricum until Diocletian's reforms, when it became a part of Epirus Nova in the 4th century AD. Christianity spread to the Polog region during the later period of Roman rule and reached the region relatively early. St Paul preached the Gospel in the region.

The earliest references to the division of Polog in what is today "lower" and "upper" can be found in the Alexiad written by Anna Komnene when she mentions two Pologs, and the earliest records to the division of Polog into specifically "lower" and "upper" in the 12th century. Serbian medieval sources also make a distinction between a "lower" and "upper" Polog but most commonly they refer to "the two Pologs", the region was put under firm control of the Serbian state in the reign of King Milutin where the first cases of pronoia in the Serbian state were recorded Some of the earliest recorded settlements in Polog are from the 11th century with only one having the rank of city, Gradec, other settlements recorded in the 13th century are Tetovo, Banica/i, Rečica, Lisec, Točil, Leskov- jane, Nerašte, Radeevo. Of these settlements Htetovo would become the central hub of the region, today known as Tetovo. Because of the famous Holy Mother of God monastery in the vicinity the city will experience rapid progress, while the previously larger cities of Gradec and Lešok would stagnate and become villages. The region including the city of Tetovo would remain under the dominance of the Serbs until the arrival of the Ottomans. Between the years 1348–1353, Albanians are mentioned by Serbian king Stefan Dušan as farmers and soldiers in the district of Tetovo within the Polog region. In 1337, Dušan restored the Monastery of St Mary (Lešok Monastery) and gifted the monastery the local Albanian villages in the region, as well as the Nanov Dol highlands. Dušan barred everyone, particularly the Albanians, from grazing the sheep in these highlands.